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For instance, DNA methylation of key ferroptosis-related genes, such as GPX4, FSP1 and NFE2-like BZIP transcription factor 2 (NRF2) genes, has been shown to affect the expression of these genes, which participate in the regulation of ferroptosis[20-22]

Carlsson, A

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Peak areas were integrated in the extracted ion chromatograms of GSH dithiomethane (m/z of 354.074 0.03, retention time of 2.9 min), GSSG (m/z of 613.160 0.03, retention time of 2.0 min), SF-GSH (m/z of 485.112 0.03, retention time of 3.1 min) and GSH-EE dithiomethane (m/z of 382.110 0.030, retention time of 4.1 min)

Judging from the clinical outcomes, these effects have multiple positive implications

It underscores both the implications for current practice and the priorities for future research aimed at transforming care for individuals with HCU