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Endoscopic biopsies of colon mucosa werecollected from normal subjects, from macroscopicallynormal tissue of patients with inactive and active ulcerative colitis, and from inflamed tissue ofpatients with active ulcerative colitis

Functional annotation highlighted genes potentially involved in AFB1 detoxification, including predicted cytochrome P450, epoxide hydrolase (LAP2), glutathione-S-transferase (URE2), and the ABC transporter (YCF1), suggesting pathways for AFB1 activation, glutathione conjugation, and vacuolar sequestration