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Most infusions take between 30 and 60 minutes, depending on formulation and dosing

ChAT catalyzes the synthesis of ACh from choline (Ch) and acetyl-CoA (AcCoA), while AChE degrades ACh to terminate synaptic signaling

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Translational interpretation must therefore remain cautious: while animal and in vitro models provide strong mechanistic plausibility, definitive connections to human disease will require longitudinal biomonitoring and well-designed epidemiological studies

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[DOI] [PMC free article] [PubMed] [Google Scholar] [75].Hulett FM, Bookstein C, Jensen K