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Description
ALP, alkaline phosphatase

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Cigarette Smoke - Smoking creates a heavy oxidative load that glutathione has to constantly work against

Evidence suggests that the equivalent of a vicious cycle can occur where microglia produce oxidative products and then increased intracellular reactive oxygen species (ROS), in turn, activates a redox-sensitive NF-B to provoke excessive neuroinflammation
[PubMed: 13608407] 66

Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts
