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They observed that FXR-depleted mice had an uncontrolled immune response upon active intestinal inflammation, and upon introduction of a synthetic FXR, they observed counter-regulatory effects on innate immunity and attenuation of organ injury

Without adequate B12, the body cannot produce enough healthy red blood cells, resulting in reduced oxygen delivery to tissues and organs

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J Pharmacol Sci 95:1926 Prkacin I, Separovic J, Aralicia G, Perovic D, Gjurasin M, Lovric-Bencic M, Stancic-Rokotov D, Staresinic M, Anic T, Mikus D et al (2001) Portal hypertension and liver lesions in chronically alcohol drinking rats prevented and reversed by stable gastric pentadecapeptide BPC 157 (PL-10, PLD-116), and propranolol, but not ranitidine

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