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A controlled study (PMID: 7777652) found that DSIP did not significantly affect CRH- or meal-induced ACTH and cortisol secretionindicating DSIP does not measurably blunt the human cortisol response, contrary to stress-protective effects suggested by some animal studies

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Peptide detection poses challenges for anti-doping programs, while increasing consumer availability accentuates the need for supplement quality assurance
