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Approximately, 12% of the total oxygen is converted to superoxide radicals
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Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy

doi: 10.1016/S0021-9150(99)00297-X

On top of this, glutathione production drops significantly as we age, leading to an inevitable imbalance of too much toxic stress and inflammation and not enough antioxidants to counter it
For short-term experiments where the peptide will be reconstituted and used immediately, the standard acetate form is perfectly effective and has the most historical research data behind it