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This reaction is catalyzed by betaine-Hcy methyltransferase (BHMT) and this pathway is mainly restricted to liver and kidney

Consistently, in patients with mutations in the N-acetyl transferase ( NAT ) gene, which is involved in the metabolism and detoxification of free radical species, age-related hearing loss occurs more frequently than in healthy subjects [24]

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doi: 10.1002/pro.3119

Nutrition and retina, in Nutrition and the Eye

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