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575 Similarly, the loss of mitochondrial complex I leads to a decrease in the ratio of NAD + /NADH and can inhibit the activity of Sirt3, thereby enhancing the protein acetylation and mPTP sensitivity

The weight loss curves had not plateaued at week 26, suggesting that longer treatment periods would yield even greater reductions

PQQ (Pyrroloquinoline Quinone) PQQ is a vitamin-like compound that supports mitochondrial health in two ways

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Meister and Tate, 1976