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doi: 10.1073/pnas.052706899

They are adjunctive, not foundational

Additionally, it supports heart health by reducing the risk of heart disease and stroke

The intrinsic factor then binds with B12, facilitating the uptake of B12 in the small intestines.[ref] Without intrinsic factor, you cant absorb B12 from animal proteins

Drugs and Lactation Database (LactMed) [Internet]