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(2017) 9(11):e1

In all four cases, appropriate development requires the tight control and regulation of ECM assembly, modification and degradation

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Cet effet de modulation gnique stend aux voies lies la rponse aux plaies, aux facteurs de croissance et aux mcanismes anti-fibrotiques, suscitant un intrt croissant dans les tudes de biologie rgnrative

In pregnant rabbits given once weekly subcutaneous doses of 0.01, 0.03, or 0.1 mg/kg tirzepatide (0.01-, 0.06-, and 0.2-fold the MRHD) during organogenesis, pharmacologically-mediated effects on the gastrointestinal system resulting in maternal mortality or abortion in a few rabbits occurred at all dose levels