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FAS is an important enzyme of fatty acid biosynthesis which in the presence of NADPH catalyzes the condensation of acetyl-CoA and malonyl-CoA to generate palmitic acid 63

[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Siafis S., ray O., Wu H., Schneider-Thoma J., Bighelli I., Krause M., Rodolico A., Ceraso A., Deste G., Huhn M., et al

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It also appeared that tobacco use affects the quantitative mRNA expression of CYP1B1, the induction of which may be influenced by genetic polymorphisms ( The enhanced CYP2E1 expression and activity (Villard et al., 1998