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These remain proposed effects, not confirmed clinical outcomes

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However, glutamate dose-response analysis of GluK5(Y683I) showed no major changes in apparent affinity (EC 50 ) compared to GluK5(wt), when measured in the presence of a binding-impaired GluK2 subunit GluK2(T690V) (Fig

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Both scenarios make skin more susceptible to breakouts, but the peptide isn't causing the problem