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Individuals taking anticoagulants, immunosuppressants, or other medications affecting the vascular system should be particularly cautious, given BPC-157's effects on blood vessel formation and nitric oxide signaling

However, it differs from other forms of PCD in that ferroptosis is based on divalent iron and leads to cell death by promoting lethal accumulation of intracellular lipid peroxides [12]

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BPC-157 interacts with the nitric oxide (NO) system, which regulates vascular tone and neural signaling (Sikiri et al., J Pharmacol Sci, 2014)
