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Nat Commun (2016) 28:12015

These cover innovative formulation strategies, chemical coupling with hydrophobic ligands or nanoparticles that exhibit targeted affinities, modifications of amino acid backbone, as well as the utilization of enzyme inhibitors, permeation enhancers, and mucoadhesive polymers [94]

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Ethics declarations The experimental protocol followed the guidelines of the Declaration of Helsinki, and it was approved by the University of Granada Institutional Review Board (IRB approval, 438/CEIH/2017)

Proper pre-reconstitution storage is just as vital as post-reconstitution care