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Description
Here they present a cell-free, multiple hydrogen-bond crosslinked hydrogel loaded with tannic acid and Kartogenin with ultra-durable mechanical properties and stage-dependent drug release behavior to promote cartilage regeneration.

It combines two medications: hydrochlorothiazide, a thiazide diuretic that helps the body get rid of excess salt and water, and triamterene, a potassium-sparing diuretic that helps the body retain potassium

The peptide's action stimulates the work of macrophages and fibroblasts, leading to faster elimination of inflammation and wound healing by releasing growth factors that promote further migration and proliferation of fibroblasts

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This cell-permeable peptide antagonist blocks the interaction of FOXO4 and p53.

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