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Dynamic regulation of synaptic GABA release by the glutamate-glutamine cycle in hippocampal area CA1

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Malnutrition or malabsorption causes decreased insulin signaling which reduces GHR expression and blocks the GH signaling pathway leading to IGF-I expression (GHR uncoupling), while GHs metabolic actions on lipolysis and gluconeogenesis are unaffected

doi: 10.1111/jgh.12021

Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species

Pauwels, F., Vergauwen, B., Vanrobaeys, F., Devreese, B