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Research progress on the role of PKM2 in the immune response

Mild, transient fluid retention/edema and joint or muscle pain, each reported more often on MK-677 than placebo in the same trial, linked to elevated GH and IGF-1

This protocol was amenable to other diterpenes, and ent -kaurane and abietane natural products were also synthesized

However, the studies did not include assessments of dietary intake either before or after the treatment periods, leaving it uncertain whether changes in diet may have affected the outcomes
