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The clinical relevance of these motility semen parameter changes relate to evidence that suggests hyperactivation is necessary for fertilization, and progressive motility is necessary for movement through the female reproductive tract

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In a comprehensive 2018 review published in Current Neuropharmacology , Sikiric and colleagues examined the brain-gut axis interactions of BPC-157 and noted that doses ranging from as low as 10 ng/kg to 10 g/kg produced observable effects in various experimental models (PMID: 28707506)

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