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NAC provides the raw material for your body to produce glutathione naturally, which some researchers argue is more effective because intracellular glutathione synthesis ensures the antioxidant ends up where its needed (inside cells)

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A similar hair regeneration experiment was also conducted in diabetic C57BL/6 mice

Thus with the help of a glutathione assay, GSH/GSSG ratio is determined and the level of oxidative stress can be measured

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Therefore, NAC is not always a reliable way to boost systemic glutathione