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Eur J Pharmacol 2020;888:173574
We could construct a network of enzyme/transporter-metabolite interaction pathways where each pathway could be evaluated in terms of metabolic adaptability, allowing quantification of the changes
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It is expressed in the apical membrane of the proximal tubule of the human kidney ( Function of URAT1 ( SLC22A12 ) URAT1 plays an important role in urate reabsorption in the kidney
