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BCAAs are transported into the mitochondria through SLC25A44, where mitochondrial BCAT (BCATm) catalyzes reversible transamination of BCAAs to produce the branched-chain ketoacids (BCKAs) -ketoisovalerate (KIV), -keto--methylvalerate (KMV), and -ketoisocaproate (KIC)

[DOI] [PMC free article] [PubMed] [Google Scholar] 115.Sakusic A., Rabinstein A.A

Today, peptides remain an active and rapidly evolving area of scientific research, offering insight into how complex biological processes are initiated, regulated, and optimized

[DOI] [PMC free article] [PubMed] [Google Scholar] 299.Dambrova M, Makrecka-Kuka M, Vilskersts R, Makarova E, Kuka J, Liepinsh E
CD47, which typically acts as a dont eat me signal expressed by live cells, is upregulated by apoptotic cells within human and murine atherosclerotic plaques, allowing them to evade uptake by phagocytes

Emerging strategies, including nanoformulation, liposomal encapsulation, and structural modification, aim to improve bioavailability and tissue delivery
