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In recent years, non-pharmacological treatments such as physical therapy, exercise therapy, cell therapy, and nanoparticles have shown great potential in mitigating disease progression and alleviating clinical symptoms

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When wounded, Nrf2 / mice have been shown to display delayed healing and prolonged inflammation in the affected area, with expression of proinflammatory cytokines altered such that although their expression levels are lower than those of wild-type mice their production continues for a significantly longer time period [94]

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10.1038/nature05448 Nature 83 WangH.ZhouC.SunX.JianY.KongQ.CuiK.et al (2018)

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Figure 4 The islets are highly vascularized within the pancreas, which is crucial to maintain their capacity to secrete insulin quickly in response to elevated blood glucose

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498 Similarly, enteral nutrition initiated within 48 h has been linked to shorter hospitalization durations

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