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Gut Microbes 14 , 2083905 (2022)

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Hypothalamic-Pituitary-Thyroid Axis TH is secreted from the thyroid gland under the regulation of the hypothalamic-pituitary axis ( Figure 1 )

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Moreover, the high dimensionality of the metabolomic profiles, relative to the available training population sample sizes, introduces a residual risk of false discovery, despite stringent feature selection and validation across independent external datasets