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SAEs relatedness to the administration of vitamin B 12 or placebo will be judged by the investigator/designee, the Ethics Committee and the DSMB who will have access to all relevant investigations, clinical assessments and if require unblinding allocated interventions

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Research linking inositol directly to sleep is limited, especially when compared to L-theanine or magnesium

Perimenopause Prescribing in 2026: Why Compounding Is the Missing Piece Estrogen-based hormone replacement therapy prescribing has more than doubled since 2018