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Nature 505 , 412416 (2014)
[DOI] [PubMed] [Google Scholar] Diaz Vivancos P., Wolff T., Markovic J., Pallard'O F.V., Foyer C.H
10.1097/MPH.0000000000001203 [DOI] [PubMed] [Google Scholar] Malik S
Aging 11:115126
In a survey of human clinical case studies, 5.3 mg/day was the lowest oral dose at which local gastrointestinal irritation was seen
Furthermore, despite its good safety profile, SAMe has been contraindicated in patients with bipolar disorder owing to its induction of mania or hypomania [191]
