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2,3,6 A thorough investigation is recommended in patients presenting with gynecomastia, as multifactorial etiologies may be involved

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doi: 10.1093/FEMSRE/FUU010 192 TsigosCChrousosGP

Chronic MP exposure induces structural damage to the intestinal mucosa, manifesting as villus atrophy, crypt architectural disorganization, and accumulation of immune cells, including lymphocytes and plasma cells 31