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Within a year, Marlboros market share had grown from less than 1% to the fourth biggest brand in the American domestic cigarette market, with net profits of $20 billion

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Tobacco use also suppresses the expression of angiogenic markers such as vascular endothelial growth factor (VEGF), leading to decreased blood supply and impaired vascularization, which are crucial for bone healing

Urine tests can detect nicotine for several days after use and are commonly used in workplace and insurance screenings

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