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[DOI] [PubMed] [Google Scholar] 229.Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM

Hcy interacts with cysteine-825 residues situated on the pro-insulin receptor within the endoplasmic reticulum (ER), thereby disrupting the formation of initial disulfide bonds

These modifications stabilize the molecular structure, allowing it to mimic the amphipathic alpha-helix of the native hormone

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