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Evidence suggests multiple interrelated pathways of liver injury: Nicotine-induced injury : Nicotine is metabolized in the liver via CYP2A6, where it activates 7-nicotinic acetylcholine receptors (7-nAChR), leading to oxidative stress, mitochondrial dysfunction, and pro-fibrotic signaling [36, 125, 126]

Archived from the original on 7 February 2011

From a prevention standpoint, additional research is needed to identify potential agents that can reduce lung cancer risk especially among former smokers

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Try to remember that insomnia is a short-lived side effect of quitting, and this can eliminate some of that burden

e-cigarettes are the most common source of non-cigarette tobacco among pregnant women 6