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223,224 Notably, GLP-1 RAs enhance nutrient recognition by increasing insulin sensitivity, regulating mTOR signaling, and promoting autophagy, among other mechanisms, as previously mentioned

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However, these metabolic benefits are often counterbalanced by complications such as hypoglycemia, stemming from mechanisms like altered nutrient absorption, exaggerated insulin responses, and increased incretin secretion [16, 17]

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Gastroenterology 117:99105 Layer P, Holst JJ, Grandt D, Goebell H (1995) Ileal release of glucagon-like peptide-1 (GLP-1)

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Bioinformatics 25 , 14221423 (2009)

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