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RF-409 is not expected to be universally effective across all classes of IR mutations but is well suited to variants that retain receptor expression and intrinsic kinase activity while being defective in insulin binding or ligand-induced activation, as illustrated by the IR D707A mutation

Allulose, by contrast, doesn't cause blood sugar spikes, which keeps insulin levels at bay, and may therefore help improve insulin sensitivity

Ian Strand, a West Point graduate and Army combat veteran who served as an infantry officer before going into medicine

Archived from the original on 17 April 2024
