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However, because glucagon-like peptide-1 receptor agonists work to slow gastric emptying, a safety concern has been raised in patients undergoing deep sedation or general anesthesia regarding gastric aspiration, and considering their long half-life in the blood, they are difficult to manage in the perioperative period

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Two leading glucagon-like peptide-1 (GLP-1) receptor agonists for obesity and type 2 diabetes Novo Nordisk A/Ss semaglutide (Wegovy/Ozempic) and Eli Lilly and Co.s tirzepatide (Mounjaro/Zepbound) are advancing in China after taking the U.S

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