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Volume overload correlates with cardiovascular risk factors in patients with chronic kidney disease
however, LEAD-6 was open-label and the insulin glargine arm in LEAD-5 was open-label since the basal insulin dose was individually titrated
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The studies reported on secondary outcomes, including all-cause mortality, fatal and non-fatal myocardial infarction (MI) and stroke, as well as hospitalisation for heart failure
Dealing with limited overlap in estimation of average treatment effects
