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[30] Severe or worsening abdominal pain , particularly if localized to the upper abdomen and radiating to the back, may indicate pancreatitisa rare but serious adverse effect included in the Warnings and Precautions section of GLP-1 medication labels

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The selectivity comes from receptor distribution: visceral fat expresses more GH receptors than subcutaneous tissue, making it more responsive to GHs lipolytic signals

Cigna also announced a specialized GLP-1 pharmacy, which will soon go live for patients