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Vitamin B12 is vital for several key bodily functions, including the formation of healthy red blood cells, neurological system support, and DNA synthesis

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When theres a vitamin B12 deficiency, individuals might experience mood fluctuations and difficulties in focusing

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Thus, it is possible that the senescent phenotype drives the accumulation of CD38 + inflammatory cells, which modulate the availability of NAD + precursors, and plays a crucial role in the metabolism of nicotinamide nucleotide (Figure 5) (65)