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Vitamin B12 shots are given to prevent or treat disorders or health complications caused by vitamin B12 deficiency.

Malabsorption (insufficient intake of vitamin B12in the intestine) due to insufficient production of intrinsic factor (a protein that is formed in the gastric mucosa and is required for the absorption of vitamin B12), Diseases in the end section of the ileum (part of the small intestine), e.g

Vitamin B12 injections, commonly used to treat deficiencies, can occasionally lead to adverse effects, most notably hypersensitivity reactions such as anaphylaxis

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