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DrugDrug Interactions Only one study reported the effect of other drug on pharmacokinetic parameters of oral semaglutide.47 A randomized study investigated the effect of omeprazole (40 mg once-daily) on the pharmacokinetics of oral semaglutide in 54 healthy subjects

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Overall, the efficacy of semaglutide in weight reduction was demonstrated in patients both with concomitant T2Dspecifically in STEP 2 [39], which included only patients with T2D, as well as in STEP 6, 7, and 10, which included both patients with and without T2D [4143]and without diabetes (STEP 1, 3, 4, 5, 8, and 9) [13, 38, 40, 4446]

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