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At the turn of the century two dermatologists, Adolf Jarisch, an Austrian, and Karl Herxheimer, published papers on observations that patients receiving treatment for syphilis would develop specific symptoms due to the treatment

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Cystathionine-beta-synthase (CBS) CBS is the first and rate-limiting enzyme in the reverse transsulfuration pathway (Figure 1) in which L-cysteine is generated from methionine

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After incubation, 1 ml of ookinete culture was taken and mixed with 1 ml of 4% paraformaldehyde (PFA) and incubated at room temperature for 15 min