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[34] Vitamin K is required for the gamma-carboxylation of specific glutamic acid residues within the Gla domain of the 17 vitamin Kdependent proteins

Pharmacology of OR has been described with the message/address model: the ligand is composed of two parts, one carrying the activity (agonist or antagonist) at the different subtypes of OR, the message and one part, the address, conveying selectivity toward a given OR (Portoghese et al., 1990)

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