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Direct Drug Interaction Risks Between Opioids and GLP-1s Medical literature documents that combining opioids with GLP-1 receptor agonists can increase the risk of severe nausea, vomiting, constipation, and delayed gastric emptying beyond what either drug causes alone

What are the statistics of NAION among Wegovy users

2012Sep;55(9):24562468

Main use: blood sugar control in type 2 diabetes

When those signals support restarting, protocols generally re-enter below the prior peak dose

This initial wave of side effects tends to be the strongest and most bothersome, though it often improves significantly by day 10
