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The value proposition is subtraction: what have you removed

In a randomized clinical trial published in JAMA Psychiatry, semaglutide reduced alcohol craving and improved some drinking outcomes versus placebo in adults with alcohol use disorder

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These findings are of significant clinical relevance, given that substantial calorie deficits, while effective for short-term fat loss, pose a risk of nutritional deficiencies, metabolic disorders, and adverse side effects such as sarcopenic obesity [8, 10, 23]