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The study protocol received approval from the Ethics Committee at Tehran University of Medical Sciences (IR.IUMS.TMU.REC.1400.015) and was registered with the Iranian Clinical Trials Registry (IRCT20220929056058N1) (15/01/2024)

58 Median time to the development of a full symptom complex of frequency, urgency, and pain was reported to be two years in one study

revealed that inhibiting autophagy with chloroquine or ATG5/ATG7 siRNAs significantly enhanced EGFR-TKI-induced cytotoxicity in NSCLC cells (Han et al

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