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3163, for lawsuits alleging that Ozempic caused non-arteritic anterior ischemic optic neuropathy, or NAION, a serious condition that can result in sudden and permanent vision loss

However, uncertainties persist regarding the prospects for adverse liver effects that might be inherent to the mechanism of action, as stabilisation of hepatic steatosis would be unwelcome

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This partial success illustrates how peptides at the boundary may achieve approval under restricted indications while still confirming the fundamental constraints (Melmed et al., 2015)