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The subsequent procedures have been described in a previous study 21

FDG allows for a comprehensive assessment of whole-brain glucose utilization, although it is important to recognize that FDG-PET signals do not specifically target mitochondrial integrity

Age may influence therapeutic efficacy, as a meta-analysis by Liu et al
Reduced frontal activation during verbal fluency task in chronic hepatitis C patients with interferon-based therapy as measured by near-infrared spectroscopy

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