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There has been concern that certain processing methods of mate, such as drying the leaves with smoke, may introduce polycyclic aromatic hydrocarbons (the carcinogenic substances also found in grilled or smoked meats)

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Racial/ethnic differences in cutpoints were observed: 5 ng/mL for non-Hispanic White individuals, 6 ng/mL for non-Hispanic Black individuals, and 1 ng/mL for Mexican-American individuals

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After some time, I got licorice or candy-like sweetness, and it started to hurt my nose