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A key underlying feature of PCOS is insulin resistance, which exacerbates the hormonal imbalances and metabolic complications seen in this condition
Recent epidemiological data indicate an overall incidence of MASLD ranging from 46.1 to 46.9 new cases per 1,000 person-years, with a prevalence estimated at 30.05% to 32.4%

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Unsurprisingly, it has been estimated that healthcare expenditure of European countries for overweight, obesity and related comorbidities might require approximately 8% of total national budgets between 2020 and 2050 4
