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While the overall frequency of liver enzyme elevations across the over 1,400 participant safety database of danuglipron is in-line with approved agents in the class, a single asymptomatic participant in one of the dose-optimization studies experienced potential drug-induced liver injury which resolved after discontinuation of danuglipron

But while theyre effective, many users experience mild skin irritation, redness, or tenderness at the injection site

This marks a significant shift in access to semaglutide, one of the most effective medications for type 2 diabetes and weight management.

Facts about treatment and pharmacology here.