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Lancet 2018;392:1519-29

Chronic Kidney Disease (CKD): Several companies are investigating the potential benefits of GLP-1 drugs in slowing the progression of CKD, a common complication of diabetes

doi.org/10.3390/receptors4010002 Batista AF, Forny-Germano L, Clarke JR, et al

In a meta-analysis of 60 studies involving 60,077 T2D patients, GLP-1RAs marginally reduced the UACR in comparison to placebo and other antidiabetic agents, but resulted in no clinically relevant changes in eGFR (Kristensen et al., 2019)

[DOI] [PubMed] [Google Scholar] 58.Cao L.J., Li D.F., Feng P., Li L., Xue G.F., Li G., Hlscher C

12 Although larger-scale studies are yet to explore the effects of GLP-1 RAs on cardiac structure and function, available evidence suggests that GLP-1 RAs may improve systolic and diastolic function in individuals with T2D who are at high risk of CVD and reduce infarct size after acute MI