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Trends Endocrinol Metab (2020) 31(4):27686

Tan YV, Waschek JA

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89 Ectopic expression of IDH2 R172K in CD4 + T cells was shown to lead to markedly increased levels of 2-HG, histone-3 lysine methylation and 5-methycytosine, and decreased 5-hydroxymethylcytosine